Beckwith-Wiedemann Syndrome is an overgrowth syndrome that is generally present at birth. It is disorder that causes the body to over grow certain parts of the body. The real cause for this disorder is not known, but it may be caused due to genetics. This disorder greatly increases the risk of cancer at the childhood, which is a very critical period as there is an increased rate of tumor development. Large tongues, mid abdominal wall defects, low blood glucose after birth and above average body size are the common features of this syndrome. This syndrome affects 1 in 12000 infants worldwide. Some tests like blood tests, study of the chromosomes, MRI or CT scan and ultrasound of the abdomen can be done to determine this condition. Abdominal wall defects can be treated by surgery. If the child has low blood glucose in the first month of its lffe, it may lead to permanent brain damage. So, this requires neonatal hypoglycemia. If the tongue protrudes so much that the infant cannot close its mouth, it causes speech difficulties, respiratory problems and feeding difficulties. An abdominal ultrasound in a gap of 3 months for 8 years of age is recommended. There is no known way to prevent this syndrome, but families who would like to have another child can atend genetic counselling classes.
How does Beckwith-Wiedemann Syndrome look like?
It is an overgrowth of certain parts of the body.
Take a look at some pictures of people suffering from Beckwith-Wiedemann Syndrome.